If you only have one full day to spend in Charlottesville... hike the Moormans River, spend the afternoon having a lunch picnic at local wineries then dinner at Three Notch'd Grill before returning to The Inn at Sugar Hollow Farm. See the map.
Head to Monticello for a tour then lunch at historic Michie Tavern and then visit Jefferson, Trump and Blenheim wineries. Go Downtown for dinner at Citizens Burger Bar, Zocalo, Fleurie or Fellini's (or any other great option!) See Map.
Head north west to tour Montpelier. Lunch at Early Mountain Vineyard, taste wine at Barboursville and Horton Vineyards, then Mas in the Belmont District for dinner. See Map
Take the back way up to Swift Run Gap. Drive down to the South Entrance of Shenandoah National Park stopping for lunch along the way and hiking and the views. Dinner at Blue Mountain Brewery on the way home. See Map.
The Blue Ridge Parkway and Humpback Rocks hiking, then lunch at Wild Wolf Brewery, a visit to Bold Rock Cidery, Silverback Distillery, or vineyards such as Flying Fox, Afton Mountain, or Veritas depending on your tastes. Finish the day with dinner at Restoration in Crozet, VA. See Map